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Article Type

Article

Abstract

Bronchiectasis is a chronic heterogeneous lung disease with poorly understood pathogenic processes and variable contributing factors. The aim of this study is to assess the prevalence and the impact of vitamin D deficiency in bronchiectasis patients. A cross-sectional study of 40 Baghdad teaching hospital respiratory diseases consultant outpatient clinic patients with verified bronchiectasis was undertaken between 2022 and 2023. 40 healthy, demographically matched controls were also studied. A detailed history, comprehensive physical examination with respiratory emphasis, and vitamin D level evaluation were done. Vitamin D levels were categorized as deficient (< 20 ng/ml), insufficiency (20–29.9 ng/ml), and adequate (≥ 30 ng/ml). Patients were categorized as frequent exacerbates (≥3 times/year) or non-frequent exacerbates (<3 times/year). Symptom intensity was further divided into mild, moderate, and severe. We studied 40 bronchiectasis patients, 21 of them were male and 7 had comorbidities. The mean age, BMI, ESR, and CRP for included patients were 39 years, 23.945 kg/m2, 9.65 ml/hr, and 0.234 mg/dL. Group vitamin levels averaged 19.68 ng/ml. Average annual exacerbation, BSI, Bhalla, and FEV1 scores were 1.95, 6.325, 14.275, and 85.8%. Bronchiectasis patients and healthy controls had similar demographic and clinical features except for vitamin D and CRP. Exacerbation number, BSI score, Bhalla score, and FEV1 correlated with vitamin D but not ESR or CRP. In conclusion, Vitamin D insufficiency is common in bronchiectasis patients and healthy people and is linked to poor symptom severity, radiological abnormalities, and lung function.

Keywords

Bronchiectasis, Vitamin D, Exacerbation, severity, Deficiency

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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