•  
  •  
 

Article Type

Article

Abstract

Enteric fever or typhoid fever is a life-threatening multi-system infection common in underdeveloped nations. Blood cultures give unequivocal proof of infection and are the cornerstone of laboratory diagnosis. RDTs detect IgM within 2–3 days after infection. IgM indicates a recent infection, while IgG indicates a distant infection. Study goal: To examine the role of serological tests as a first test while waiting for blood culture results and to demonstrate IgM and IgG accuracy in recognizing typhoid illness in children. Cross-sectional research with analytic component done at the Karbala Children's Teaching Hospital. The research included 81 children with typhoid-like symptoms, including fever, headache, vomiting, and stomach discomfort. The investigation yielded hematological, biochemical, and serological outcomes. A blood culture was performed to verify the diagnosis. Most study participants (78/96.3%) had positive anti-salmonella IgM findings, whereas 32/39.5% did. Blood cultures diagnosed 47 (58%) study individuals with typhoid fever (Salmonella infection). Positive blood cultures provide 43 (91.5%) ciprofloxacin-susceptible isolates. Anti-salmonella IgM has 95.7% sensitivity and 5.6% specificity. 70.8% anti-salmonella IgM accuracy. Anti-salmonella IgG had 38.3% sensitivity and 61.1% specificity. Anti-salmonella IgG had 44.6% accuracy. The major sign of enteric fever is a high body temperature, along with anorexia, vomiting, stomach discomfort, and headache. The main risk factor is water availability. Serological tests with a positive IgM result serve a significant role in diagnosing typhoid fever and commencing antibiotic treatment early while waiting for blood culture results.

Keywords

Girls, Women, Premenstrual dysphoric disorder, Environmental factors

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Download

Share

COinS